millions treated for hypothyroidism at risk for lung cancer millions treated for hypothyroidism at risk for lung cancer

A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.'. In the United States, autoimmune thyroid disease (Hashimoto thyroiditis) is the most common cause of hypothyroidism, but globally lack of iodine in the diet is the most common cause. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer BUT, this is the first I have heard of the potential risk of lung cancer in those who take Synthyroid. They then correlated drug sales with cancers, eliminating the contribution of age and smoking for lung cancer risk. Most of the time, doctors tell patients treated with LT4 that any side effects will be temporary and almost ineluctable, and are usually dealt with through dose reduction. Once I got on the medication, the symptoms disappeared. Cancer Risk After Radioactive Iodine Treatment for - PubMed Reddit and its partners use cookies and similar technologies to provide you with a better experience. Article published in Wakeup-World.Com. Or, simply look at what the young-adult,T-score based definition of osteoporosis and osteopeniahas done to convert millions of healthy middle-age and older women into drug-treatable patients, or, what the lipid hypothesis of cardiovascular disease causation has done to create a 30-billion dollar a year market in statin drugs, to fully appreciate the harms of overdiagnosis and overtreatment. I think part of sharing information here on Inspire is the discussions about the articles we share. millions treated for hypothyroidism at risk for lung cancer Hypothyroidism can also lead to swelling of the tongue, hoarse voice, and sleep apnea. CRF encompasses physical, emotional, and/or cognitive tiredness; is related to cancer or cancer treatments; and interferes with multiple dimensions of health-related quality of life (1-3).CRF is poorly understood, underrecognized, and undertreated. [9] [10] [11] Although we should never forget that LT4 is a life-saving thyroid hormone replacement, and that one should not exclude that the pathological reason that leads to the prescription of LT4 could favor the lung cancer development also. (February 2002). So I will leave it as a simple thank you for passing this along. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism. Other research indicating that increased thyroid activity (hyperthyroidism) contributes to lung cancer pathogenesis was presented, including: Recently T4 has been reported as one of the several endogenous factors capable of supporting proliferation of lung cancer cells. J Endocrinol Invest. Perhaps she and I could co-author? Correlation is when two things seem to happen at the same time, in the same place, and/or in the same population. May be of interest: Study: Millions Treated for Hypothyroidism At Risk for, Non-small cell lung cancer - Adenocarcinoma, Non-small cell lung cancer - Squamous cell, Top 5 Questions to Ask Your Lung Cancer Doctor, Patient & Caregiver Network Member Resources, Not A Member Yet? It took over five years before the someone figured out my ongoing symptoms were due to hypothyroidism. Other research indicating that increased thyroid activity (hyperthyroidism) contributes to lung cancer pathogenesis was presented, including: The authors also cite animal experimental research which has shown that T4 increases the oxidative stress[6] and spontaneous pulmonary metastases in mice. Is This the Real Reason You're Exhausted All the T Why An Alkaline Approach Can Successfully Treat Ca We're Losing the War on Cancer- Here's Why. However, that information will still be included in details such as numbers of replies. Capmatinib (Tabrecta) is the first FDA-approved MET-targeting medication for treating metastatic NSCLC. [7] They also elaborate on a mechanism of T4-induced lung tissue toxicity: [I]n rats lung the deiodination of LT4 is the lowest compared to all the other tissues. Thank you for bringing it to our attention. Or that it was the many years of not being diagnosed with hypothyroidism, courtesy of daft blood test ranges, before finally tipping a TSH over 5 (or even 10) before treatment is commenced, by which time the damage is done. It is very tormenting (for me anyhow) to not know why I got this disease. The authors delved deeper into the reason why oxidative stress taking place during T4 treatment is particularly linked to lung cancer only: The hypothesis could be that in lungs the increase of hypoxia-induced factor (HIF-1) which is determined by T4 can make oxygen much more available, increasing locally the oxidative stress together with a dangerous angiogenesis stimulation. I invite those interested to read it and perhaps we can have a discussion on this study. In fact, it is the high levels of T4 that make them more susceptible to cancer. The article also stresses that too many people are being given the diagnosis of either hypo or hyperthyroidism. They also noted that oxidative stress is one of the causes of chronic diseases and cancer. I have posted the link, so you can see if it has any merit. That's all. The authors did not study whether individuals who took Synthroid actually developed lung cancer later in life. Non-ASPS articles which could be relevant. [7] They also elaborate on a mechanism of T4-induced lung tissue toxicity: "[I]n rats lung the deiodination of LT4 is the lowest compared to all the other tissues. Not what people like me are saying. ", Cure Alveolar Soft Part Sarcoma International, COMPLETED - Dana Farber Vaccine Clinical Trial (GVAX), Axitinib and Pembrolizumab (Keytruda) in Miami, US, TECENTRIQ (atezolizumab) by Genentech, Treatment of Non-Resectable Primary Tumor, Immune checkpoint inhibitors ICI (PD-1 and PD-L1 targeting drugs), Toxicity, problems and potentiation strategies, Treatment response criteria and evaluation/scanning problems/rare cases, treatment discontinuation/re-treatment, Side effects/complications of the local ablations, High intensity focused ultrasound (HIFU), Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer, http://www.greenmedinfo.com/blog/study- ng-cancers. "Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)", International Journal of Human Nutrition and Functional Medicine, Osteoporosis Is Scurvy of the Bone, Not Calcium Deficiency, 6 Bodily Tissues That Can Be Regenerated Through Nutrition, 7 Simple Ways to Unclog Your Arteries Naturally, Herbal Cream Clears 87.7% of HPV Cases Naturally, How WHOLE Turmeric Heals the Damaged Brain. The authors also cite animal experimental research which has shown that T4 increases the oxidative stress[6] and spontaneous pulmonary metastases in mice. 2 Hypothyroidism is the most common type of thyroid disorder, and women's risk of hypothyroidism is five to eight times higher than that of . Physician/Author on Facebook. If I can help someone, fine. Importance: Whether radioactive iodine (RAI) therapy for hyperthyroidism can increase cancer risk remains a controversial issue in medicine and public health. Hypothyroidism can cause depression and, without treatment, the symptoms intensify and directly affect the mental state. I am having a lot of trouble making any sense of this study. weight loss, anorexia) was made many years ago together with an over production of both T4 and T3. In discussing their findings, the authors noted that they could not exclude the possibility that the condition of hypothyroidism could favor the development of lung cancer. [9] Otto T, Fandrey J: Thyroid hormone induces hypoxia-inducible factor 1 gene expression through thyroid hormone receptor /retinoid x receptor -dependent activation of hepatic leukemia factor. The authors expanded on their findings further: "However, the impression we get from our experience in epidemiological studies monitoring[12] is that this drug should be prescribed more cautiously. I discovered this article published in Wakeup World. Privacy Policy. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer at LifeGivingStore.comRed Light Therapy - Hydrogen Water Generators - Cascara Sagrada - Vitamins, Minerals & Amino Acid Supplements - Cocoa Products - Handcrafted Soaps - Grass Fed Organs & Glandulars - Nano Soma. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer The relationship between levothyroxine use and cancer risk is largely underdetermined. Currently, the best practical approach is to base treatment decisions on the degree of TSH elevation, thyroid autoimmunity, and associated comorbidities. I don't believe there are thousands of people on to high a dose of t4, so why does it feel they are hyper? It does not necessarily imply one thing caused the other. It does not seem to quantify the increased risk, and it keeps saying it is hyperthyroidism that causes the oxidised stress. A place for patients and relatives. Garlic Beats Drug in Detoxifying Lead Safely From How Yoga and Acupuncture Enhance HealthNew Resear Health Nuts: Seeds And Nuts You Should Eat Every Day. I posted it to see what anyone had to add. Oops I have just bought my first jar of marmalade in over ten years! bear in the big blue house characters; colne times obituaries this week Menu Toggle. ", That study is like a fishing expedition. Endocrinology 2008, 149:22412250. Levothyroxine and cancer risk study : Hi sorry to - Thyroid UK Now, I will bring it to the attention of my Endocrinologist. What I am personally saying issince I personally have a disease that may kill me, I sure as heck have every right to find out ALL I can about it. undefined will no longer be visible to you including posts, replies, and photos. In my view the paper isn't worth the pixels used to display it on a screen. PMID: 23539727, [16] Alan R Gaby. Acta Endocrinol 1988, 118:460464. 1). Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study. arizona lockdown status today; tiktok unblocked from school; samantha and savannah concepcion LOL. View the data on our Hypothyroidism Research page. Assessment of oxidative stress and its balance has not been taken into consideration up to now as it should be. [13] Hollowell JG, Staehling NW, Flanders WD, et al. [8] This means that the amount of LT4 reaching the lungs following an external supplementation cannot to be transformed into LT3 as in the other tissues, and make lungs very vulnerable to possible toxic effects of LT4. Even acute bouts of stress and subclinical adrenal insufficiency can cause cyclical downshifts in thyroid function. New Cholesterol Drug Guaranteed to Prematurely Kil Beware the Walgreens travel vaccination scam. Metab.87 (2): 48999. Keri Topouzian, D.O. Physician/Author - Facebook Levothyroxine is a widely prescribed medication for the treatment of an underactive thyroid. Given the clear role that selenium deficiency plays in preventing the conversion of T4 to the far more biologically active form of thyroid hormone known as triiodothyronine (T3), which can cause an elevation of thyroxine-stimulating hormone (TSH), why call a mineral deficiency-induced decrease in T4 a monolithic disease entity such as "hypothyroidism"? [4], More recently DI activity in lung cancer was found to be lower than in peripheral lung tissue.[5]. Note: Only a member of this blog may post a comment. [11] Wan J, Chai H, Yu Z, Ge W, Kang N, Xia W, Che Y: H1F-1 on angiogenic potential in human small cell carcinoma. Symptoms can include fatigue, shortness of breath with exercise, and decreased ability to exercise. A distorted idea of human nature is sold when people are treated as "the market. Sub-laboratory hypothyroidism and the empirical use of Armour thyroid. According to data from the National Health and Nutrition Examination Survey, years 1988-1994, [13] while 0.3% of the American population exhibits overt symptoms of hypothyroidism, 14 times more (4.3%) have so-called 'subclinical' hypothyroidism only detected via blood work. 'A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low . Study: Millions Treated for Hypothyroidism at Risk of Lung Cancer Endocrinology 1985, 117:12011208. [4] Ratcliffe JG, Stack BH, Burt RW, Radcliffe WA, Spilg WG, Cuthbert J, Kennedy RS: Thyroid function in lung cancer. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional. Yes, lung cancer patients can have these symptoms, but so do patients who have other cancers. Medical Authoritys System Kills: FDA-Approved Dru Cognitive Impairment, Memory Loss and Alzheimer's Soy Lecithin: How It Negatively Affects Your Healt Cannabis Oil Cures Cancer -Lincoln Horsley's Story New Information Dissolves Illusions About Vaccines Grounding Helps Thin Dangerously Thick Blood and F Tart Cherries Relieve Osteoarthritis Pain, Lieberman's Massive Connections To Big Pharma, Utopian 'Harvest Your Own' Groceries Coming Up. This relatively symptom-free reservoir of 'hypothyroid' cases provides a veritable gold mine of potential office visits, billable services and drug prescriptions. A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' Brit Med J 1978, 1:210212. It looks at correlations, as if they had any merit on their own. You may not notice signs or symptoms of the disease. [2], The observation that patients with small cell carcinoma of the lung often present symptoms suggestive of hyperthyroidism (i.e. Those with the greatest risk of developing thyroid disorders are women who have a family history of the disease. I cried with joy when I found out there was something really wrong with me. I hope that with increased knowledge we will all find the right road. Salt, Sugar, Fat: 15 Shocking Facts From the Book Dear Doctor, Do You Really Know What Vaccines Cont Colloidal Gold: Discover the Benefits and Wonders, Scientists Explain Why HPV Vaccines Are Unsafe. hyperthyroidism. Comp Biochem Physiol C Toxicol Pharmacol 2002, 133:475481. ", Orsomeone posts something about, say a diet or supplement and them some people think they are something it "Cures lung cancer.". Study: Millions Treated for - The Wellness Institute | Facebook Respiratory system Hypothyroidism weakens the respiratory muscles and decreases lung function. Patients with undertreated hypothyroidism at higher risk for longer Different strokes for different folks for sure! Cancer-related Fatigue in Lung Cancer: A Research Agenda: An Official radioactive treatments. I'm just saying the evidence presented in this article isn't very strong, and more study is needed to show Synthroid causes lung cancer. Patients with incomplete information (n = 127), preexisting hypothyroidism or levothyroxine replacement before initiation of ICI therapy (n = 11), or other factors known to contribute to thyroid dysfunction after immunotherapy (n = 17) were excluded (Fig. The increasingly global medical-industrial complex has begun to co-opt all aspects of the natural human bodily life cycle, and all the organ systems within it, as potential targets of medical surveillance and intervention, not excluding the human thyroid. (They noted that this age range corresponds to more than 80% of the consumers of the drug and to about 99% of all malignant cancers). According to data from the National Health and Nutrition Examination Survey, years 1988-1994, [13] while 0.3% of the American population exhibits overt symptoms of hypothyroidism, 14 times more (4.3%) have so-called subclinical hypothyroidism only detected via blood work. weight loss, anorexia) was made many years ago together with an over production of both T4 and T3. Indeed, research indicates that hypothyroid patients treated with T4 replacement, that is sufficient to maintain a normal serum TSH, actually have serum free T4 that is higher than in untreated normal patients and may not result in appropriately normal serum free T3 concentrations. Correlation is NOT causation. rocket fuel, pesticides, fluoride, which induce low thyroid function. At GreenMedInfo.com, we have indexed plenty of peer-reviewed research on over 30 natural substances, including nutrients and minerals, which may help to resolve low thyroid function, and conversely, over 30 unnatural substances, e.g. Thyroid dysfunction after immune checkpoint inhibitor treatment in a single-center Chinese cohort: a retrospective study But what can be done for patients who are at low [2], The observation that patients with small cell carcinoma of the lung often present symptoms suggestive of hyperthyroidism (i.e. J Clin Endocrinol Metab. Results indicate that treatment with levothyroxine was linked with significantly increased mortality (hazard ratio = 1.19). One of the main drawbacks of administering T4 in isolation is the possibility that it will not convert adequately to T3, and will therefore 'back up' causing excessive T4 activity, i.e. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer. Study: Millions Treated for - Healing Lyme Disease | Facebook Article published in Wakeup-World.Com. millions treated for hypothyroidism at risk for lung cancer El almacenamiento o acceso tcnico es estrictamente necesario para el propsito legtimo de permitir el uso de un servicio especfico explcitamente solicitado por el abonado o usuario, o con el nico propsito de llevar a cabo la transmisin de una comunicacin a travs de una red de comunicaciones electrnicas. Allthewebsites Directory - A niche web directory offering website promotion and other webmaster resources. Whereas a patient who had suboptimal thyroid function, but did not have noticeable symptoms, is suddenly given pharmacological doses of synthetic T4 and suddenly experiences the wide range of acute, adverse health effects associated with a now hyperactive and/or increasingly disrupted thyroid, as a result. This relatively symptom-free reservoir of hypothyroid cases provides a veritable gold mine of potential office visits, billable services and drug prescriptions. Millions of people who were not only wrongly diagnosed with 'cancers' and subsequently aggressively treated for them with chemotherapy, radiation and surgery, are now being told that they would have been better left undiagnosed and untreated. There is also the very real possibility that T4 will not only not properly interact with thyroxine cellular receptors, but will block out what remaining natural levothyroxine the thyroid is still producing (and whose conformational state is far more health-promoting), essentially acting as an endocrine disrupter at the very moment that it is acting as intended as a 'TSH suppressor.' Compression of the trachea, which may be positional, can occur with nodular goiters and thyroid cancer, and the latter can metastasize to the lungs. Indeed, research indicates that hypothyroid patients treated with T4 replacement, that is sufficient to maintain a normal serum TSH, actually have serum free T4 that is higher than in untreated normal patients and may not result in appropriately normal serum free T3 concentrations. END TIME NEWS, A CALL FOR REPENTANCE, YESHUA THE ONLY WAY TO HEAVEN. Treating Elderly for Subclinical Hypothyroidism Can Boost Mortality Rates Forgot account? http://www.greenmedinfo.com/blog/study-millions-treated-hypothyroidism-risk-l Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer, Iodine Supplementation Support by VWT Team. Biomedicine today is awash in controversy associated with the overdiagnosis and overtreatment of asymptomatic populations. They also noted that oxidative stress is one of the causes of chronic diseases and cancer. [4] Ratcliffe JG, Stack BH, Burt RW, Radcliffe WA, Spilg WG, Cuthbert J, Kennedy RS: Thyroid function in lung cancer. Just another excuse for keeping us on doses that are too low. The Goji Berry: The Jolly Super Food That Gives Yo How to Prevent and Treat Insect Bites Without Hars Supreme Court Rules Drug Companies Exempt From Law Spain Study Confirms Hemp Oil Cures Cancer without Wheatgrass Turns Gray Hair Back to Its Natural Color, Medicinal Cannabis Used To Prevent Cancer Growth. Cookie Notice Subclinical hypothyroidism is defined by an elevated serum thyroid-stimulating hormone (TSH) level along with a normal free thyroxine (T4) level. Share your experience, learn from others. [15] [16]There is also the more logical option of support the bodys thyroid-hormone producing capabilities using the thyroxine precursor L-tyrosine, a basic amino acid with a relatively high margin of safety. Si as lo deseas puedes revisar el resto de nuestros contenidos para encontrar lo que buscabas o directamente utilizar nuestro buscador. A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). [11] Wan J, Chai H, Yu Z, Ge W, Kang N, Xia W, Che Y: H1F-1 on angiogenic potential in human small cell carcinoma. [14] K A Woeber. Risk of cancer in longterm levothyroxine users: Retrospective Gestionar el consentimiento de las cookies. [14] In other words, you can 'normalize' the main clinically measurable parameter associated with 'low thyroid function,' i.e. A study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' Hashimoto's disease progresses slowly over the years. I have sent the link that I read today. Endocrinology 2008, 149:22412250. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. Post author By ; Post date jaripeo hillsboro oregon 2021; what task do they have at camp westerbork on millions treated for hypothyroidism at risk for lung cancer on millions treated for hypothyroidism at risk for lung cancer The omnipresent environmental contaminant perchlorate, an ingredient in jet fuel, is also a primary cause of hypothyroidism, but is almost never tested for by the conventional endocrinologists in their patient evaluations. [12] Cesarone MR, Belcaro G, Nicolaides AN, Incandela L, De Sanctis MT, Barsotti A: San Valentino epidemiologic project. Overtreatment, of course, is the hallmark danger of overdiagnosis. For a better experience, please enable JavaScript in your browser before proceeding. I will respond more later onBut I will briefly say I was on Synthyroid from 1993 to 2011. Based just on this article, I think the study's conclusion that Synthroid may cause an increase in lung cancer risk is premature. Marketed as superior to traditional glandular forms extracted from pigs (whose endocrine glands are far more bioidentical than any other animal we know of) due to the dose-to-dose standardization of the so-called active ingredient T4 versus the natural variations in hormone concentrations found in the real thing, which incidentally contains a wide range of additional hormones including T1, T2, T3, all of which are vitally important. 2002 Feb ;25(2):106-9. Furthermore, the geometric expansion of hypothyroidism cases in the past decade only thinly conceals an agenda to promote the synthetic form of T4 known as levothyroxine sodium (trade name Synthroid), since with each new 'disease' case the patient is converted into a lifelong customer. When a high-risk patient presents with one or more lung nodules, the path ahead and next steps seems obvious. Methods: The study group included 35 patients (15 women, 20 men, 65.8 7.1 years) with NSCLC in stage IIIB (n = 16, 45.7%) and IV (n = 19,54.3%) who were treated with nivolumab. JavaScript is disabled. Even in the mildest form, hypothyroidism affects the heart. Tokushima J Exp Med 1991, 38:2535. The great open sky of imagination: for those who u Fermented Foods: Top 8 Reasons to Eat Them. Intuition and Trust: a Personal Journey Through Ancient Pathways, Meditation, Yoga, Grounding & Mindfulness, Levothyroxine and lung cancer in females: the importance of oxidative stress, 2013 announcement by a National Cancer Institute, T-score based definition of osteoporosis and osteopenia, 30-billion dollar a year market in statin drugs, Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). PLoSone 2011, 11:e27547. Could be another marmalade how would we know? The authors of the study pointed out that levothyroxine (T4) treatment can lead to medication-induced (iatrogenic) thyroid over-activity (hyperthyroidism) and oxidative stress that can lead to a significant patient discomfort. Eventually, the decline in thyroid hormone production can result in any of the following: Fatigue and sluggishness. Angiology 2000, 51:S65S68. However, they pointed out that the opposite was recently described, and that "hypothyroidism reduces theaggressiveness of some cancers because of the presence of thyroid hormone receptors oncancer cells, and spontaneous hypothyroidism may delay onset or reduce aggressiveness ofcancers."[1]. I very much appreciate the information you shared. This is a horrible disease that ravages the body. I bet in the previous discussion, if there was one, we would have concluded it was likely that it was because people are generally not put on enough levothyroxine. Modern Medicine, Part I: How Healing Illness Becam Is your body getting too acidic? However, they pointed out that the opposite was actually described, and that hypothyroidism reduces the aggressiveness of some cancers because of the presence of thyroid hormone receptors on cancer cells, and spontaneous hypothyroidism may delay onset or reduce aggressiveness of cancers.[1]. [8] This means that the amount of LT4 reaching the lungs following an external supplementation cannot to be transformed into LT3 as in the other tissues, and make lungs very vulnerable to possible toxic effects of LT4. However, the study looked at the incrase of ALL lung cancers, not SCLC, so that data does not correlate with this study.